This study attempted to investigate the effects of Sojagangkitang and Gamisojagangkitang on the variation of lung thiobarbituric acid(TBA) value, tracheal glycoprotein, serum sodium ion contents, serum potassium ion contents ; immediatly type allergy reaction, delayed type allergy reaction in rats and mice.
The results were as follows:
1. Sojagangkitang and Gami-sojagangkitang revealed significant effect on immediatly type hypersensitivity responds to histamine.
2. Sojagangkitang and Gami-sojagangkitang revealed significant effect on delayed type hypersensitivity responds to picryl chloride.
3. Sojagangkitang and Gami-sojagangkitang revealed significant effect on delayed type hypersensitivity responds to SRBC, effect of Gami-sojagangkitang was outstanding.
4. Lung thiobarbituric acid(TBA) value was decreased with statistical significance.
5. Sojagangkitang and Gami-sojagangkitang revealed decreasing effect on Tracheal glycoprotein contents, effect of Gami-sojagangkitang was outstanding.
6. Sojagangkitang and Gami-sojagangkitang revealed decreasing effect on phenol red excretion of respiratory tract.
7. Viscosity of mucine solution was decreased in proportion to increasing dosage of the Sample.
8. Serum contents was not recognized significance.
9. Sojagangkitang and Gami-sojagangkitang revealed decreasing effect on Serum contents, effect of Gami-sojagangkitang were outstanding.
According to the above results, it seems that Sojagangkitang and Gami-sojagangkitang can be applied for asthma, chronic obstructive pulmonary diseases, allergic respiratory diseases.
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